Esophageal squamous cell carcinoma (ESCC) analysis has revealed the role of long intergenic noncoding RNA (lincRNA) uc002yug.2 in carcinogenesis, particularly through the modulation of the nuclear AS environment to favor the RUNX1 isoform RUNX1a and reduce CEBPα, an event found to have predictive potential over prognoses in ESCC patients [61]. The gene discussed is RUNX1; the disease is esophageal squamous cell carcinoma.