FOXO3 and cancer: Forkhead box O3 (FOXO3), an important member of the FOXO subfamily of transcription factors, has shown to transcriptionally upregulate several autophagy-related markers such as unc-51-like autophagy activating kinase 1 (ULK1), Beclin-1 and microtubule associated protein 1 light chain 3 (LC3) [12], controlling autophagy even in cancer cells [13].