Moreover, quercetin supplementation also reduced markers of oxidative stress (indicated by plasma MDA levels) and inflammation (measured as plasma ratios of TNF-α /IL-10 and IL-8/IL-10 as pro-inflammatory markers) in the blood of sarcoidosis patients, with the effects appearing to be more pronounced when the levels of the oxidative stress and inflammation markers were higher at baseline. This evidence concerns the gene TNF and sarcoidosis.