Mechanistically, the IL-15 antifibrotic role was associated with the induction of interferon-γ-responsive invariant natural killer T (iNKT) cells or T-helper cell type 17 suppressor RORγ+ Treg cells in chronic pancreatitis models [18] and in allergen lung fibrosis models [17] respectively. The gene discussed is RORC; the disease is pulmonary fibrosis.