In 2020, the FDA approved brexucabtagene autoleucel for patients with mantle cell lymphoma [238,239] while, in 2021, it approved B-cell maturation antigen (BCMA)-directed autologous CAR T cells (idecabtagene vicleucel) for patients with multiple myeloma [240]. Here, TNFRSF17 is linked to mantle cell lymphoma.