For example, S deficiency [9,10,11] is associated with an increase in plant contents of molybdenum (Mo), selenium (Se), and vanadium (V) because root sulfate transporters, which are up-regulated under S deficiency, are also able to mediate transport of these structurally similar anions. This evidence concerns the gene SLC26A2 and hyperinsulinemic hypoglycemia, familial, 4.