PDE7B and type 2 diabetes mellitus: The study also revealed that 102 of the differentially methylated genes, including cyclin-dependent kinase inhibitor 1A (CDKN1A), phosphodiesterase 7B (PDE7B), septin 9 (SEPT9) and exocyst complex component 3 like 2 (EXOC3L2), were differentially expressed in T2D islets [103].