In these individuals, only DNA methylation at the loci within cg06500161 (ABCG1) and cg02650017 (PHOSPHO1), but not at cg18181703 (SOCS3), cg11024682 (SREBF1) and cg19693031 (TXNIP), in blood DNA was related to the risk of T2D in subsequent years [96]. This evidence concerns the gene SOCS3 and type 2 diabetes mellitus.