Closer characterization of the subpopulations present in the skin showed high expression levels of the hair follicle (HF)-associated genes, such as Krt27, Krt17, Hoxc13 and Wnt5a in the major three subpopulations (HF/SEB1, HF/SEB2, HF/SEB3) (Supplementary Figure S2) [55,56,57,58,59,60,61]. The gene discussed is KRT17; the disease is hydrops fetalis.