The sequencing of RNAs in human airway epithelial cells undergoing EMT showed that miR-133a is significantly overexpressed in these cells [136], forcing these cells into spontaneous EMT, through the downregulation of the grainyhead-like 2 (GRHL2) gene, an epithelial transcription factor involved in several disorders, such as the ectodermal dysplasia/short stature syndrome [137] and deafness autosomal dominant 28 [138]. The gene discussed is GRHL2; the disease is ectodermal dysplasia syndrome.