STAT3 and neoplasm: It can inhibit the activity of protein kinase B, Janus-activated kinase 2 (JAK2), p21-activated kinase (PAK), 3-phosphoinositide dependent kinase 1 (PDK1), phosphatidylinositol 3-kinase (PI3K), signal transducer, and activator of transcription 3 (STAT3), surviving, and X-linked inhibitor of apoptosis (XIAP) of tumor cells [8,10,11,12,13].