In contrast to constitutively expressed MMP-2, MMP-9 is inducible, and represents one of the most important proteinases that mediates tumor progression in human lung cancer [38], gliomas [39], pancreatic cancer [40], head and neck cancer [41], prostate cancer [42], gastric cancer [43], and breast cancer [44]. The gene discussed is MMP2; the disease is familial pancreatic carcinoma.