Finally, to evaluate the engrafted fetal liver tissues from DPPIV-positive rats in a Fischer 344 rat model of liver cirrhosis, we examined the maturity of the engrafted fetal livers by immunohistochemical staining for CD31, cytokeratin 19 (CK19), hepatocyte nuclear factor-4 alpha (HNF-4α), and albumin. Here, PECAM1 is linked to cirrhosis of liver.