A study was carried out in the control group with sham surgery (WT + PBS), in simulating Alzheimer’s disease in wild-type animals (WT + Aβ), in NLRP3 knockout animals with sham surgery (NLRP3 KO + PBS) and in NLRP3 knockout mice with the introduction of beta amyloid (NLRP3 KO + Aβ). The gene discussed is NLRP3; the disease is early-onset autosomal dominant Alzheimer disease.