Following stimulation, the altered sub-cellular localization of TAAR1 suggests variable TAAR1 function that may be dependent on the state of macrophage polarization, thereby implicating TAAR1 as a novel target through which inflammatory cellular processes such as migration and proliferation, both of which are associated with the neuroinflammation occurring in an active MS lesion. The gene discussed is TAAR1; the disease is myeloid sarcoma.