The screening experiments using the multiplex bead assay revealed a reduced production of several cytokines including GM-CSF and tumor necrosis factor-alpha (TNF-α) and chemokines such as CCL3 and CCL7 from pre-miR-877-3p-transfected RA-FLS compared to those from control RA-FLS (Supplementary Table S1). This evidence concerns the gene TNF and rheumatoid arthritis.