The top 10 enriched pathways included proteoglycans in cancer (hsa05205), axon guidance (hsa04360), Hippo signaling pathway (hsa04390), pathways in cancer (hsa05200), ErbB signaling pathway (hsa04012), Rap1 signaling pathway (hsa04015), N-glycan biosynthesis (hsa00510), Ras signaling pathway (hsa04014), renal cell carcinoma (hsa05211), and glioma (hsa05214) (Table 4). The gene discussed is EGFR; the disease is renal cell carcinoma.