BHLHE41 and androgen insensitivity syndrome: In addition, among the clinicopathologic findings in LUAD cases, the expression of BHLHE41 protein was also associated with AIS histology (p < 0.001), lack of pleural invasion (p = 0.026), T factor (T1) (p = 0.013), and stage (IA) (p = 0.013) (Table 2).