DNM1L and Alzheimer disease: They demonstrated that blockade of the mitochondrial fission dynamin-like protein 1 (DLP1, which is another name for Drp1), by a genetic manipulation with a dominant negative DLP1 (DLP1(K38A)), its knock-down with siRNA-DLP1, or inhibition of mitochondrial division with mdivi-1 attenuated mitochondrial functional defects observed in AD cybrid cells [219].