Finally, the “prostate cancer” pathway also includes DEGsSD that are relatively specific to the (human) prostate (SRD5A2, KLK2, NKX3-1 and CREB3L4), proto-oncogenes (EGFR, PDGFRA, PDGFRB, NRAS) and druggable candidates (PIK3CD, CTNNB1, PIK3CG, CDKN1A). The gene discussed is NKX3-1; the disease is Familial prostate cancer.