To further explore the involvement of RIPK4 in human cutaneous melanoma progression we conducted metadata analysis of RIPK4 mRNA levels in 83 clinical specimens (GDS 3966), 31 primary melanoma and 52 metastatic melanoma specimens using the Gene Expression Omnibus (GEO) database (https://www.ncbi.nlm.nih.gov/geo, accessed data 15 June 2020). The gene discussed is RIPK4; the disease is metastatic melanoma.