VEGFA and cancer: Anthocyanidins may decrease cancer cell proliferation by targeting receptor tyrosine kinases (RTKs), examples of which include epidermal growth factor receptor (EGFR), platelet-derived growth factor receptor (PDGFR), and vascular endothelial growth factor (VEGF)/VEGF receptor (VEGFR) and modulating Ras/mitogen-activated protein kinase (MAPK) and phosphatidylinositol-3-kinase (PI3K)/Akt signaling pathways [23,24].