SQSTM1 and Merkel cell skin cancer: Additional functional experiments conducted in MCC cells indicated that (i) LT/sT expression upregulates miR-375; and (ii) miR-375 targets two autophagy genes, including Autophagy Related 7 (ATG7) and Sequestosome-1/ubiquitin-binding protein p62 (SQSTM1/p62) [124].