The cells analyzed were the immortalized non-malignant mesothelial cell line, MeT-5A, the MM cell lines, ONE58, JL-1, and H-Meso-1, a subline of the osteosarcoma cell line, 143B (143B +/+; uPARAP positive control), and a negative control in the form of 143B uPARAP knock-out cells (143B -/-; see Materials and Methods). This evidence concerns the gene MRC2 and osteosarcoma.