ETV6 and acute lymphoblastic leukemia: For example, the ETS gene ETV6 is fused with different partner genes by specific translocations in lymphoblastic and myeloid acute leukemias, and NKL homeobox gene NKX2-5 is aberrantly activated via juxtaposition to an enhancer region of BCL11B in T-cell acute lymphoblastic leukemia (T-ALL) [17,18].