While the extent of severe brain infarct measured on the day of HI induction was similar between the study groups, the progress of brain infarct measured at 5 weeks after HI induction was significantly attenuated only with dose 3 (approximately 1 × 105 cells), but not with dose 2 (approximately 5 × 104 cells) or dose 1 (1 × 104 cells) BDNF-eMSCs or naïve MSCs (1 × 105 cells) (Figure 5B). The gene discussed is BDNF; the disease is brain infarction.