BDNF and brain infarction: HI-induced severe brain infarct and histological injury scores were not significantly attenuated in naïve MSCs (approximately 1 × 105 cells) and dose 1 (approximately 1 × 104 cells) BDNF-eMSCs transplantation, and showed a tendency to be attenuated without statistical significance with dose 2 (approximately 5 × 104 cells) BDNF-eMSCs, and significantly attenuated only with dose 3 (approximately 1 × 105 cells) BDNF-eMSCs transplantation (Figure 3B,D).