Since BDNF is known to be a critical factor for neuronal survival in various disorders including focal ischemia, hypoglycemia, meningitis, and IVH [11,24,28,29,30], we transfected the human BDNF gene to generate BDNF-eMSCs, preserving their phenotypic, paracrine, and differentiating characteristics, and enabling large-scale production at a much lower cost [18,19,20,31]. The gene discussed is BDNF; the disease is infectious meningitis.