In another similar study, it was shown that inactive MLN-NK were presented by a subset of CD56brightCD16+ cells and NKp30 and NKG2D expression levels were negatively correlated with the number of tumor cells in the infiltrated lymph nodes in metastatic melanoma [70], indicating the possible reason of decreased MLN-NK cells cytotoxic activity. This evidence concerns the gene KLRK1 and neoplasm.