It was shown that a high level of IFN-γ secretion by NK cells is positively correlated with the therapeutic response in chronic myeloid leukemia (CML) [16], while a decrease in the secretory function of NK cells was associated with the high risk of myelodysplastic syndrome development [17]. The gene discussed is IFNG; the disease is chronic myelogenous leukemia, BCR-ABL1 positive.