For example, the presence of the soluble form of B7-H6 (sB7-H6), the NKp30 ligand, has been detected in the peritoneal fluid of patients with ovarian cancer, metastatic gastrointestinal stromal tumor, neuroblastoma and hepatocellular carcinoma [35,74,80,81]. This evidence concerns the gene NCR3 and hepatocellular carcinoma.