Figure 1a (upper panel) shows the expression and co-localization of NF-kBp50 and PPARγ in the nucleus of hepatocytes of normal human liver tissue. In human HCC tissue, NF-kBp50 is in both nucleus and cytoplasm (Figure 1a, lower panel), while PPARγ is found accumulated in the cytoplasm. Fluorescence intensity was quantified in both cell compartments and represented in Figure 1b. Meanwhile, Figure 1c shows the quantification of cell nuclei positive for the double labeling PPARγ/NF-kBp50, and it is observed that both factors are mostly expressed in the nucleus of normal liver tissue. This evidence concerns the gene PPARG and hepatocellular carcinoma.