A small study aimed at identifying MGM-specific proteins in the cerebrospinal fluid (CSF) from four MGM patients and four patients with a non-brain tumor found increased levels of apolipoprotein E (ApoE), apolipoprotein J precursor (ApoJ), and alpha-1-antitrypsin (AAT), and reduced levels of prostaglandin D2 synthase 21 kDa (PTGDS), transthyretin precursor (TTR), and β-2-microglobulin precursor (β2M) [48]. The gene discussed is CLU; the disease is brain neoplasm.