Moreover, other pathways such as glycogen synthesis, glutamate/glutamine and fructose metabolism, FGFR2 signaling, interferon gamma response, ER protein processing and PPAR signaling were exclusively enriched in PD and not in DLB, being a novel source of differential features across alpha synucleinopathies (Figure 6A–C). Here, FGFR2 is linked to Lewy body dementia.