GNRH1 and endometriosis: The aim of this review is to present, based on recent literature, data on a new class of medical drugs, namely oral gonadotropin-releasing hormone (GnRH) antagonists, for the management of symptomatic endometriosis, a common chronic inflammatory disease causing pain and infertility [1,2,3] and affecting between 5% and 10% of women of reproductive age [1,3].