Female sex; older age; comorbidities, namely ischemic heart disease, diabetes mellitus, atrial fibrillation, chronic heart failure, peripheral arterial disease, asthma, chronic obstructive pulmonary disease (COPD), major depressive disorder, Parkinson’s disease, rheumatoid arthritis, and insomnia; and use of antiplatelet agents, benzodiazepines, anticoagulants, NSAIDs, acetaminophen, insulin, calcium channel blockers, diuretics, and metformin were determined to be significant risk factors for dementia. This evidence concerns the gene INS and congestive heart failure.