TIMP2 and acute kidney injury: Therefore, the AKI prevention strategies in our study were stratified according to biomarker levels with more complex measures and nephrology involvement in subgroups with elevated biomarker levels (TIMP2 × IGFBP7 ≥ 0.3) and a lower degree of intervention with fast-track ICU discharge pathway in the subgroup with negative biomarkers (TIMP2 × IGFBP7 < 0.3).