Furthermore, among 18 patients with a positive test result for SARS-CoV-2 genetic material, only 2 (11.11%) did not produce antibodies directed against it—this included a 12 month-old child with IgG and IgA deficiency and a patient with Rubinstein-Taybi syndrome and IgA, IgM and IgG deficiency, who was also treated with convalescent plasma during the acute phase of the disease. This evidence concerns the gene CD40LG and Decreased circulating IgG concentration.