IL17A and systemic lupus erythematosus: Apart of the predominance of female gender among SLE participants in the present study and previous ones [8,48], estrogen has been reported to stimulate the secretion of pro-inflammatory cytokines such as “interleukin-17 and interferon-α”, which are implicated in SLE etiopathology, either through “the modification of key transcription factors in inflammation or through the regulation of miRNA expression” [49].