In order to improve the mathematical prediction of an emerging infection, we performed a multinominal logistic regression with five variables: approach (1–6, ordinal), preoperative mean CRP (numerical), day of maximum CRP (numerical), gender (dichotomous), and failure to decline on day 5 (dichotomous), leading to a dynamic sensitivity and specificity, depending on a specific cut-off. The gene discussed is CRP; the disease is infection.