For example, patients with herpes simplex encephalitis frequently develop anti-NDMAR and other neural autoantibodies in CSF in direct relation to the degree of neuronal damage [27], and there is evidence of anti-NMDAR autoantibodies targeted to subunits other than GluN1-ATD in the serum of patients who had suffered a stroke [28]. The gene discussed is GRIN1; the disease is herpes simplex encephalitis.