According to the current data, the predictors of severe coronavirus pneumonia are age over 65 years old, classic vascular risk factors, immunodeficiency conditions, such laboratory markers as D-dimer, CRP, LDH, troponin, ferritin, CPK, lymphopenia, and some other conditions that have been shown to be associated with the disease in various studies [18,19,20,21,22]. The gene discussed is PIK3C2A; the disease is immune system disorder.