IFNG and tropical spastic paraparesis: IFNγ production by NK cells is enhanced by IL-12 [29], we thus asked whether the increased frequencies of pDC and classical monocytes producing IL-12 we observed in HAM/TSP patients (Figs 2C and 3D respectively), could be correlated to the higher frequency of CD56dimCD16- NK producing IFNγ (Fig 4F).