TLR7 and tropical spastic paraparesis: We performed single cell immunoprofiling of freshly collected blood samples from a cohort of asymptomatic carriers and HAM/TSP patients to characterize the phenotype and responsiveness of innate cell subsets after ex vivo TLR7/8-stimulation, a broad way to activate most of innate cells [14] and because, impairment of TLR7/8 signaling upon several chronic infections has been linked to diseases [15,16].