PRKN and Parkinson disease: Comparative analysis with human iNeurons datasets elaborated a PINK1/Parkin-dependent ubiquitylation signature on depolarized mitochondria in neurons comprising 49 sites across 22 MOM proteins conserved between mouse and human neurons that represent a cellular readout for PINK1 and Parkin activity and a potential proxy readout of PD-linked mitochondrial dysfunction in future studies.