LGALS1 and malignant colon neoplasm: Indeed in tissues, chemokines form gradients that enable haptotactic migration of leukocytes [42], and galectins (e.g. galectins-1, -3 and -8 (Gal-1, -3 and -8)) promote cell migration of immune cells [16], epithelial cells [43] and glioblastoma cells [44–46], respectively, as they can be suppressive in a context-dependent manner like Gal-8 with colon cancer cells [47].