LGALS3 and neoplasm: Intriguingly, this N-glycosylated cytokine itself (and also interleukin-12 but not the O-glycosylated chemokine CCL6 and the N-glycosylated CCL1) is a ligand for Gal-3 via glycan binding so that retention of IFNγ in the tumor’s extracellular matrix is made possible by Gal-3 residing there [168].