UQCRC2 and early-onset autosomal dominant Alzheimer disease: In additionto cardiomyopathy- and metabolic-related pathways, we noted thatTmem43-associated mitochondrial genes, NDUFS6and UQCRC2, are enriched in neurodegenerative disease-relatedpathways, including Alzheimer’s disease (AD), Parkinson’s disease(PD), and Huntington’s disease (HD; Table1).