High transport capacity is attributed to increased expression of MDR‐associated protein (MRP), P‐glycoprotein 1 (P‐gp) encoded by the MDR1 gene (also known as ABCB1), low‐density lipoprotein receptor‐related protein (LRP), and breast cancer resistance protein (BCRP) in cancer.231. The gene discussed is ABCB1; the disease is cancer.