Another case in melanoma shows that exosomal miR‐155‐5p induces CAF proangiogenic function via suppressor of cytokine signaling 1 (SOCS1)/Janus kinase 2 (JAK2)/signal transducer and activator of transcription 3 (STAT3) signaling pathway,40 and exosome‐mediated paracrine miR‐34a‐5p CAF triggers oral cancer cells proliferation and metastasis.41 Here, JAK2 is linked to lip and oral cavity carcinoma.