By crossing HBx‐mCherry with Src transgenic zebrafish line that expresses Src under control of the liver‐specific fabp10 promoter, HBx‐mCherry and Src double‐transgenic zebrafish were generated and 50% of the double‐line developed HCC in presence of TP53 by 14 mpf.80 Here, TP53 is linked to hepatocellular carcinoma.