TP53 and hepatocellular carcinoma: Hematoxylin and eosin (H&E) staining analysis revealed that, in wild‐type (WT) background specimens, the zebrafish resulted in hyperplasia (10%), dysplasia (5%), or steatosis (40%) at 11 months postfertilization (mpf); however, in TP53 null mutation background (TP53−/−), the zebrafish developed HCC (44%), dysplasia (17%), or steatosis (11%) at 11 mpf.