Several drugs reportedly have the potential to be senolytics, including dasatinib combined with quercetin,23 navitoclax (an inhibitor of Bcl-2 family proteins),24 inhibitors of the bromodomain and extraterminal domain (BET),25 and heat shock protein (HSP) inhibitors.26 Therefore, to establish strategies that enhance the therapeutic effects of the combination of gemcitabine and IR in malignant meningioma, we screened the combined effects of senolytic drugs with gemcitabine and IR in malignant meningioma cells. The gene discussed is HSP90B2P; the disease is Anaplastic (Malignant) Meningioma.