To determine the effects of CD2 signaling on HIV infection of blood CD4 T cells, we first quantified CD2 expression on human blood resting CD4 T cells and found that both memory (CD45RO+) and naïve (CD45RO−) T cells expressed CD2, with memory T cells naturally expressing higher levels of surface CD2 (Iglesias-Ussel et al., 2013) (Figure S1). The gene discussed is CD4; the disease is HIV infectious disease.