AGTR1, involved in the former, can promote vasoconstriction, cell proliferation, inflammation, oxidative stress, hypertrophy, and fibrosis, and angiotensin II–type 1 receptor blockers are widely used to prevent cardiac remodeling after acute myocardial infarction and heart failure (32, 33). The gene discussed is AGTR1; the disease is acute myocardial infarction.