IL1B and myocardial ischemia: Most animal experiments have shown that the expression of proinflammatory factors increases during myocardial ischemia-reperfusion (Silvis et al., 2021).IL-1β can cooperate with other cytokines to promote the activation of B and T cells, and induce the production of other inflammatory mediators, strengthen the adhesion of white blood cells and endothelial cells.