Interestingly, expression of VISTA has also been observed in different cancer types such as breast invasive carcinoma (BRCA), invasive ductal carcinoma (IDC), bladder urothelial carcinoma (BLCA), colon adenocarcinoma (COAD), kidney chromophobe (KICH), lung squamous cell carcinoma (LUSC), uterine carcinosarcoma (UCS), and skin cutaneous melanoma (SKCM). Here, VSIR is linked to cancer.