PSAT1 and cancer: YAP is also an activator of the glutamate-related aminotransferases glutamic-oxaloacetic transaminase 1 (GOT1) and phosphoserine aminotransferase 1 (PSAT1), which mediate the conversion of glutamate to α-ketoglutaric acid (α-KG), thereby stimulating cancer cell growth (Yang et al., 2018).